In this extraordinary situation, people were forced to stay at home for several weeks, with no freedom of movement. Social isolation, one of the recommended practices to prevent disease spread, may contribute to developing various problems such as depression, stress, apathy, and loneliness. The COVID-19 pandemic, on the other hand, has dramatically changed the global population. Green spaces can significantly impact people’s well-being, and many people prefer to visit them as frequently as possible for leisure, sports, relaxation, or socializing. The results of the SD method revealed that viewing yellow and red flowers resulted in a significantly higher sense of relaxation, cheerfulness, and comfort than viewing white flowers. The vigor (V) subscale and overall mood status values were significantly improved. After viewing the yellow and red flowers, the average results for each subscale of the POMS questionnaire improved. Furthermore, heart rate variability revealed that viewing yellow and red flowers increased parasympathetic nerve activity significantly. EEGs showed that the mean values of alpha relative power in the prefrontal lobe were significantly higher when viewing yellow and red flowers vs. Electroencephalograms (EEGs), heart rate variability, and skin conductivity were measured to evaluate physiological responses along with both the semantic differential questionnaire (SD) and the Profile of Mood States (POMS) to assess psychological responses. Participants looked at each flower color for 3 min. The experiment was conducted in an office-like setting with 50 participants. Therefore, this study investigates how white, red, and yellow flower colors affect individuals’ psychological and physiological well-being. Viewing flowers is expected to have similar positive effects to viewing natural scenery. The closure of green areas also affected the well-being of the individual during the COVID-19 pandemic. The global spread of COVID-19 has disrupted the normality of people’s daily lives, leading the population to social distancing and isolation.
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